Generic Name: Lynestrenol

FORMULATION
Each white tablet contains:
500 mcg Lynestrenol

PRODUCT DESCRIPTION
Lynestrenol (DAPHNE®)is a progestin-only pill that contains very low doses of a progestin similar to the natural hormone, progesterone, in a woman’s body. It consists of 28 white, round, flat, beveled edge, uncoated pill with “L” engraved on one side and plain on the other side and is intended for contraception.

Lynestrenol (DAPHNE) is a hormonal contraceptive of choice for breastfeeding women because it does not affect lactation or infant growth.

INDICATION
Lynestrenol (DAPHNE®) is indicated for contraception, notably in cases of intolerance to estrogen-progestogen combined pills or when estrogens are contraindicated. It is also recommended for lactating mothers and smoking women who require contraception.

DOSAGE AND ADMINISTRATION
1. Take one pill daily, beginning on the first day of menstrual bleeding. You may also start any day as long as you are not pregnant but use a back-up method such as a condom for the next seven days as a precaution to avoid pregnancy. Breastfeeding women can start six weeks after giving birth. Start with the pill marked with the corresponding day of the week. Follow the arrows indicated on the pack.
2. The interval between two pills should be 24 hours. Incorporate it to your daily routine-after evening meals or before going to sleep so you can easily remember to take it. A pack is good for 28 days.
3. Start a new pack the next day after taking the last pill.
4. You may continue taking the pill as long as you want to avoid pregnancy. Do not skip taking the pill even if there is a brief pause from sexual activity.
5. You should only stop taking the pill after finishing a pack; otherwise, bleeding may start.
6. Vomiting and persistent severe diarrhea can interfere with the absorption of the pill. If vomiting occurs within two hours of taking a pill, another pill should be taken as soon as possible. If the replacement pill is not taken within 3 hours of the normal time of taking the pill, or in cases of persistent vomiting or severe diarrhea, a back-up method such as condom should be used during illness and for 2 days after recovery.
7. If you missed a pill, you must take it within three hours after the 24-hour lapse to sustain its efficacy. Take the remaining pills as scheduled to avoid premature withdrawal bleeding. Follow the instructions on Missed Pills.

MISSED PILLS
The key to effective contraception is following the recommended dosage consistently.

Regularity in taking the pill is very important because contraceptive efficacy is reduced if a pill is delayed by more than three hours.

If the pill is less than three hours overdue, take it as soon as you remember. Resume taking the next scheduled pill. You will not need a back-up contraceptive method.

If the pill is more than three hours overdue, take it as soon as you remember and either abstain from sex or use condoms for the next two days. Resume taking the next scheduled pill.

If you continually forget to take your pills, ask your healthcare provider for ways to become compliant, or for another method of contraception such as an injectable which will suit you better.

ADVERSE EFFECTS
The oral contraceptive pill is one of the most researched products in the history of modern medicine, and its safety has long been established. Some women may experience side effects such as gastrointestinal disturbances, changes in appetite or weight, fluid retention, edema chloasma (melasma), allergic skin rashes, urticaria, mental depression, breast changes including discomfort and occasionally gynecomastia, changes in libido, hair loss, hirsutism, fatigue, drowsiness, insomnia, fever, headache, premenstrual syndrome-like symptoms and altered menstrual cycles or irregular menstrual bleeding. Anaphylaxis or anaphylactoid reactions may occur and rarely alterations in liver function tests and jaundice.

Manufactured by:
Pond’s Chemical Thailand R.O.P.
79 Ram-Indra Road, Anusawari
Bang Khen, Bangkok 10220, Thailand

Imported and Distributed by:
DKT Health, Inc.
80 E. Rodriguez Jr. Avenue (C5),
Bagumbayan, Quezon City
1110 Philippines